Description:
OTS-964, a thienoquinolin derivative, is a TOPK inhibitor and prabably be useful in studying anticancer agent as an analogue of OTS-514. It is still under preclinical trial. IC50: 28 nM.
- Molecular Weight:428.97
- Purity:98%
Molecular Formula:
C23H25ClN2O2S
Canonical SMILES:
CC1=CC(=C(C2=C1NC(=O)C3=C2C=CS3)C4=CC=C(C=C4)C(C)CN(C)C)O.Cl
InChI:
InChI=1S/C23H24N2O2S.ClH/c1-13-11-18(26)19(16-7-5-15(6-8-16)14(2)12-25(3)4)20-17-9-10-28-22(17)23(27)24-21(13)20;/h5-11,14,26H,12H2,1-4H3,(H,24,27);1H/t14-;/m0./s1
InChIKey:
YHPWOYBWUWSJDW-UQKRIMTDSA-N
Solubility:
10 mM in DMSO
Appearance:
Powder
Storage: -20ºC Freeze
Synonyms:
OTS964; OTS 964; OTS-964 Más detalles se encuentran
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